Blister beetles are so-called because they secrete a toxin called cantharidin as a defensive mechanism when they are threatened. Contact with cantharidin can cause blistering of the skin; ingestion can cause renal damage or even death. For this reason, it is best to avoid touching blister beetles directly. If you must move one, capture it in a container and move it that way. Fortunately, their distinctive shape makes blister beetles easy to recognize.